CombiMatrix Influenza A Detection System
can detect and accurately type influenza A strains in less than four
hours. The CombiMatrix Influenza A Detection System
accurately identifies hemagglutinin subtypes 1 through 16 and
neuraminidase subtypes 1 through 9. In addition to providing very
high-resolution information on the genotype of any previously
identified strain, the Influenza A Detection System
also provides information on novel strains of influenza A produced by
rapid mutation or recombination in the genomes which define the
serotype of these proteins. The microarray in the detection system, the
Influenza A Research Microarray, has
been tested and validated against both a representative RNA panel
consisting of all influenza A serotypes as well as against amplified
genomic material from a limited number of human and animal samples.
The Influenza A Research Microarray
identifies strains by using standard polymerase chain reaction (PCR)
with a universal influenza priming strategy and the use of multiple
(tens to hundreds of) unique, sub-type specific probes on the array.
The results are read electrochemically by the ElectraSense® Reader.
USE OF THE COMBIMATRIX
INFLUENZA A DETECTION SYSTEM
The Influenza A Detection System
is cost effective, user-friendly and reliable. The Influenza
A Detection System offers:
The ability to detect all known strains of
Influenza A, including differentiating between highly pathogenic and
comparatively less pathogenic flu strains.
A method that is highly sensitive to
mutations in the influenza virus that maximize the likelihood of
detecting new strains that have not been previously identified.
A novel way to observe mutations and
recombination events associated with changes in the genetic makeup of
the virus.
The ability to identify mixed populations
of the flu.
RE-USE OF THE COMBIMATRIX
INFLUENZA A MICROARRAY
CombiMatrix Influenza A Microarrays used in
conjunction with the ElectraSense Reader can be stripped and re-used
for a total of two times, further decreasing the cost of influenza
detection. For more information on re-use, please see the information
on the CustomArray®
Stripping Kit.
For more information fill out our contact form, telephone
800-985-2269 or email
for more information.