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SPECIAL FEATURE
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CombiMatrix
highlighted in Nature’s
Technology
Feature on DNA Microarrays
Source: Nature. 2005 Oct 20; (437):1196-1200
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Cooper J, Yazvenko N, Peyvan
K, Maurer K, Taitt CR, et al. 2010
Targeted Deposition of Antibodies on a Multiplex CMOS Microarray and
Optimization of a Sensitive Immunoassay Using Electrochemical Detection.
PLoS ONE 5(3):
e9781. doi:10.1371/journal.pone.0009781
Lodes, M. J., D. Suciu, D.
Danley, and A. McShea. 2009.
Genotyping arrays.
Integrated Analytical Systems
Series: Microarrays.
Springer. 121-138.
Cagnin, S., M. Caraballo, C.
Guiducci. P. Martini, M. Ross, M Santa Ana, D. Danley, T. West, and G.
Lanfranchi. 2009.
Overview of electrochemical DNA biosensors: new approaches to detect
the expression of life.
Sensors 9(4),
3122-3148.
Maurer K, Cooper J, Caraballo
M, Crye J, Suciu D, Ghindilis A, Leonetti JA, Wang W, Rossi FM, Stover
AG, Larson C, Gao H, Dill K, McShea A.
Electrochemically generated Acid and its containment to 100 micron
reaction areas for the production of DNA microarrays.
PLoS ONE.
2006 Dec 20;1:e34.
R. H. Liu, S. B. Munro, T.
Nguyen, T. Siuda, D. Suciu, M. Bizak, M. Slota, H. S. Fuji, D. Danley,
and A. McShea
Integrated Microfluidic CustomArray Device for Bacterial Genotyping and
Identification
Journal of the Association for
Laboratory Automation, 2006, 11, 360-367.
Grundhoff A, Sullivan CS,
Ganem D
A combined computational and microarray-based approach identifies novel
microRNAs encoded by human gamma-herpesviruses.
RNA. 2006
May; 12(5): 733-50.
Dill, K., Ghindilis.,
Schwarzkopf K.
Multiplexed analyte and oligonucleotide detection on microarrays using
several redox enzymes in conjunction with electrochemical detection.
Lab Chip,
2006; 6: 1052–1055, DOI: 10.1039/b600126b.
Andrey L. Ghindilis et al.
CombiMatrix oligonucleotide arrays: Genotyping and gene expression
assays employing electrochemical detection.
Biosensors and Bioelectronics
(2006), DOI: 10.1016/j.bios.2006.06.024.
Liu R, Lodes M, Nguyen T,
Siuda T, Slota M, Fuji H.S., McShea A.
Validation of A Fully Integrated Microfluidic Array Device for
Influenza A Subtype Identification and Sequencing
Analytical Chemistry,
2006, 78,4184-4193
Nittler M.P, Hocking-Murray D,
Foo C, Sil A.
Identification of Histoplasma capsulatum Transcripts Induced in
Response to Reactive Nitrogen Species
Molecular Biology of the Cell,
2005 October; 16: 4792–4813
Lodes M, Suciu D, Elliott M,
Stover A, Ross M, Carabello M, Dix K, Crye J, Webby R, Lyon W, Danley
D, McShea A.
Use of Semiconductor-Based Oligonucleotide Microarrays for Influenza A
Virus Subtype Identification and Sequencing
Journal of Clinical Microbiology,
2006 April; 44(4): 1209–1218
Liu R. H., Dill K, Fuji H. S.,
McShea A.
Integrated microfluidic biochips for DNA microarray analysis
Expert Review of Molecular
Diagnostics. 2006; 6(2): 253-261
Liu R.H., Nugyen T,
Schwarzkopf K, Fuji H. S., Petrova A, Siuda T, Peyvan K,
Bizak M, Danley D, McShea A.
A Fully Integrated Miniature Device for Automated Gene Expression DNA
Microarray Processing
Analytical Chemistry.
2006; 78: 1980-1986
Wells C, Chalk A.
Alternate transcription of the Toll-like receptor signaling cascade
Genome Biology
2006; 7:R10.
Maurer K, McShea A, Strathmann
M, Dill K.
The removal of the t-BOC group by electrochemically generated acid and
use of an addressable electrode array for peptide synthesis.
J Comb Chem
2005 Sep-Oct;7(5):637-40. No abstract available.
Oleinikov AV, Zhao J, Gray MD.
RNA interference by mixtures of siRNAs prepared using custom
oligonucleotide arrays
Nucleic Acids Res.
2005 Jun 7;33(10):e92.
Kumar A, Anderson B, Dill K.
Electrochemical detection for microarray IVD applications
IVD Technology
2005 May
Kumar A, Anderson B, Dill K.
Detection Technologies
IVD Technology
2005 April
Tian J, Maurer K, Tesfu E,
Moeller KD.
Building addressable libraries: the use of electrochemistry for
spatially isolating a heck reaction on a chip
J Am Chem Soc.
2005 Feb 9;127(5):1392-3.
Dill K, Montgomery DD,
Ghindilis AL, Schwarzkopf KR, Ragsdale SR, Oleinikov AV.
Immunoassays based on electrochemical detection using microelectrode
arrays.
Biosens Bioelectron.
2004 Nov 1;20(4):736-42.
Rhodes D, Yu J, Shanker K ,
Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A,
Chinnaiyan A.
Large-scale meta-analysis of cancer microarray data identifies common
transcriptional profiles of neoplastic transformation and progression
Proceedings of the National Academy
of Sciences 2004 June 22; 101(25): 9309–14
Oleinikov AV, Gray MD, Zhao J,
Montgomery DD, Ghindilis AL, Dill K.
Self-assembling protein arrays using electronic semiconductor
microchips and in vitro translation
J Proteome Res.
2003 May-Jun;2(3):313-9.
Tesfu E, Maurer K, Ragsdale
SR, Moeller KD.
Building addressable libraries: the use of electrochemistry for
generating reactive Pd(II) reagents at preselected sites on a chip
J Am Chem Soc.
2004 May 26;126(20):6212-3. No abstract available.
Dill K, Montgomery DD,
Ghindilis AL, Schwarzkopf KR.
Immunoassays and sequence-specific DNA detection on a microchip using
enzyme amplified electrochemical detection
J Biochem Biophys Methods.
2004 May 31;59(2):181-7.
Dill K, Montgomery D, Wang W,
Tsai J.
Antigen detection using microelectrode array microchips
Analytica Chimica Acta.
2004: 69–78
Rhodes D, Yu J, Shanker K ,
Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A,
Chinnaiyan A.
Large-scale meta-analysis of cancer microarray data identifies common
transcriptional profiles of neoplastic transformation and progression
Proceedings of the National Academy
of Sciences 2004 June 22; 101(25): 9309–14
Arjomand A, Kumar A
Integration of RNAi into drug discovery
2003 November
Arjomand A, Kumar A
An open-platform microarray system for R&D
2003 June

The CombiMatrix group
currently has four patents issued in the United States, three patents
issued in Europe and 80 patent applications pending in the United
States, Europe and elsewhere.
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